Former Arkansas standout Bobby Portis gets significant suspension from Bulls
Multi-dimensional approach needed for food security: president
Thousands still without power in wake of Storm Ophelia
Yankees to Send Masahiro Tanaka Against Astros in Game 1
Delhi: Five people including four women found dead in Shahdara's Mansarovar park
Human embryo gene editing has taken place in USA, claims report
28 July 2017, 12:27 | Lucy Hill
First Human Embryos Edited in US
Pioneered by scientists elsewhere in the world, primarily in China, the gene editing technique known as CRISPR (short for "clustered regularly interspaced short palindromic repeats"), a team led by Shoukhrat Mitalipov of the Oregon Health and Science University are the first known researchers to perform human embryo DNA modification in the United States.
It is important to note that none of the embryos were allowed to develop for more than a few days, and that the team never had any intention of implanting them into a womb.
"So far as I know this will be the first study reported in the U.S.", Jun Wu, who played a role in the project and is a collaborator at the Salk Institute, said to MIT.
Until now, the only three published reports of human embryo gene editing were from researchers in China. In previous attempts by Chinese scientists, CRISPR caused an editing error wherein the DNA changes they made were only taken up by some, not all, of the cells the embryos developed. The study has demonstrated that it is possible to safely correct abnormal genes that cause hereditary diseases, and used quite a number of human embryos to experiment on.
Mitalipov has always been pioneer in embryo research. Interestingly, Chinese researchers have found it hard to get the genetic changes in every cell of the embryos that they seek edit. But Mitalipov was able to "significantly" reduce mosaicism, according to MIT Technology Review.
"It is proof of principle that it can work". Along with the National Academy of Medicine, the academy stated that scientific advances make gene editing in human reproductive cells "a realistic possibility that deserves serious consideration".
The approach holds great potential to avoid many genetic diseases, but has raised fears of "designer babies" if done for less lofty reasons, such as producing desirable traits. Technology Review could not determine which disease genes had been chosen for editing. He created the first cloned monkeys in 2007 and in 2013 created the first human embryonic stem cells through cloning.
The need for it is clear, he added: "Our research has suggested that there are far more disease-associated mutations in the general public than was previously suspected".
There are many concerns around genetically engineering humans.
Currently, any effort to turn an edited human embryo into a baby in the United States is banned by Congress.
Despite such barriers, the creation of a gene-edited person could be attempted at any moment, including by IVF clinics operating facilities in countries where there are no such legal restrictions.
Antonio Candreva: 'Chelsea interest is nice'
After a few minutes of medical attention on the ground, the Spanish global walked off the pitch and did not return to the game. Speaking at a news conference in China on Friday, Conte said: "It is very important the choice".
Draymond Green facing lawsuit for alleged assault
California attorney Lisa Bloom said in a news release on Monday that she is filing a lawsuit against Green on Tuesday. Green's plea deal reduced the charges to a noise and civil infraction from a misdemeanor.
Swiss chainsaw attack was not a terrorist hit
The injured included one employee of the insurance company who suffered serious wounds, AFP reported, citing Schaffhausen police . Officers warned that Wrousis may be armed and asked anyone who sees him to contact police immediately, and to keep away from him.
Blazers trade Allen Crabbe in salary dump
Portland matched the sheet and, under league rules, needed to wait one full year to include Crabbe into a deal with the Nets. The Blazers have been rumored to be involved in the Carmelo Anthony or Kyrie Irving sweepstakes, likely as a third team.
VW executive to plead guilty in 'dieselgate' case
US prosecutors have amassed more than 4.3 million documents covering more than 40 million pages in the ongoing probe. Numerous other managers charged are believed to be in Germany, making extradition to the USA unlikely.